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Science 30 May 1969:
Vol. 164. no. 3883, pp. 1085 - 1087
DOI: 10.1126/science.164.3883.1085
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Articles

Relation of Pharmacological and Behavioral Effects of a Hallucinogenic Amphetamine to Distribution in Cat Brain

Juhana E. Idänpään-Heikkilä 1, William M. McIsaac 1, Beng T. Ho 1, George E. Fritchie 1, and L. Wayne Tansey 1

1 Texas Research Institute of Mental Sciences, Houston 77025

The hallucinogen 2,5-dimethoxy,-4-methylamphetamine, also known as STP, accumulates in specfic areas of cat brains. The unchanged compound was detected in the brain for at least 6 hours, whereas its behavioral effects lasted for about 4 hourS. The coincidental pharmacological and behavioral effects of the compound apparently indicate a relation between the anatomical distribution and action.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)