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Science 30 May 1969:
Vol. 164. no. 3883, pp. 1080 - 1082
DOI: 10.1126/science.164.3883.1080
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Articles

Postsynaptic Membrane Response Predicted from Presynaptic Input Pattern in Lobster Cardiac Ganglion

Daniel K. Hartline 1 and Ian M. Cooke 2

1 Department of Biological Sciences, Stanford University, Stanford, California 94305
2 Biological Laboratories, Harvard University, Cambridge, Massachusetts 02138

Given the pattern of impulses impinging on a neuron, it should be possible to predict its output firing pattern if enough is known about pre- and postsynaptic properties. A quantitative reproduction of the first part of this input-output conversion is reported, namely the translation of input pattern into a sequence of postsynaptic membrane potential variations.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Reliable, Responsive Pacemaking and Pattern Generation With Minimal Cell Numbers: the Crustacean Cardiac Ganglion.
I. M. Cooke (2002)
Biol. Bull. 202, 108-136
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Science. ISSN 0036-8075 (print), 1095-9203 (online)