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Science 30 May 1969:
Vol. 164. no. 3883, pp. 1073 - 1075
DOI: 10.1126/science.164.3883.1073
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Articles

Dihydroorotic Acid Dehydrogenase: Introduction into Erythrocyte by the Malaria Parasite

Robert S. Krooth 1, Kuang-dong Wuu 1, and Raymond Ma 1

1 Lawrence D. Buhl Center for Human Genetics, Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48104

Mature, circulating mammalian erythrocytes lack dihydroorotic acid dehydrogenase activity. However, we have detected activity, which appears to reside in an enzyme, in malaria parasites purified from mammalian blood.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)