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Science 16 May 1969:
Vol. 164. no. 3881, pp. 832 - 834
DOI: 10.1126/science.164.3881.832
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Articles

Actinomycin D: Uptake by Sea Urchin Eggs and Embryos

M. Michael Thaler 1, Malcolm C. L. Cox 2, and Claude A. Villee 2

1 Department of Pediatrics, University of California—San Francisco Medical Center, San Francisco 94122
2 Department of Biological Chemistry, Harvard Medical School, Boston, Massachusetts 02115, and Marine Biological Laboratory, Woods Hole, Massachusetts 02543

Actinomycin D is excluded from unfertilized eggs and developing embryos of the sea urchin Arbacia punctulata until the blastula hatches. The rate of uptake of actinomycin D by embryos doubles as development progresses after hatching to the gastrula stage.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sea Urchin Embryos Are Permeable to Actinomycin.
G. A. Greenhouse, R. O. Hynes, and P. R. Gross (1971)
Science 171, 686-689
   Abstract »    PDF »
Posttranscriptional Control in the Steroid-Mediated Induction of Hepatic Tyrosine Transaminase.
I. B. Levitan and T. E. Webb (1970)
Science 167, 283-285
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)