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Science 16 May 1969:
Vol. 164. no. 3881, pp. 828 - 830
DOI: 10.1126/science.164.3881.828
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Articles

Simultaneously Recorded Trains of Action Potentials: Analysis and Functional Interpretation

George L. Gerstein 1 and Donald H. Perkel 2

1 Departments of Biophysics and Physiology, University of Pennsylvania, Philadelphia 19104
2 Department of Mathematics, RAND Corporation, Santa Monica, California 90406

A new kind of statistical display, the joint peri-stimulus-time scatter diagram, facilitates the analysis and interpretation of two or more simultaneously recorded trains of action potentials. The display is a generalization of the cross correlation and the peri-stimulus-time histogram, and it reflects specific underlying neuronal interactions. The technique yields quantitative measures of interaction in terms of effectiveness of synaptic connections.


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