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Science 2 May 1969:
Vol. 164. no. 3879, pp. 568 - 569
DOI: 10.1126/science.164.3879.568
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Articles

Cytogenetic Effects of Cyclamates on Human Cells in vitro

D. Stone 1, E. Lamson 1, Y. S. Chang 1, and K. W. Pickering 1

1 Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts, and Worcester State Hospital, Worcester, Massachusetts

Chromosome studies on human cells in vitro have shown that the artificial sweeteners, sodium and calcium cyclamate, can induce chromosome breaks in vitro in human cells, in both leukocyte and monolayer cultures.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Chromosomal Analyses of Bone Marrow and Peripheral Blood in Subjects With a History of Illicit Drug Use.
A. P. Amarose and C. R. Schuster (1971)
Arch Gen Psychiatry 25, 181-186
   Abstract »    PDF »
Cytogenetic Studies with Cyclamate and Related Compounds.
D. R. Stoltz, K. S. Khera, R. Bendall, and S. W. Gunner (1970)
Science 167, 1501-1502
   Abstract »    PDF »
Report to the Secretary of HEW From the Medical Advisory Group on Cyclamates.
R. O. Egeberg, J. L. Steinfeld, I. Frantz, G. C. Griffith, H. Knowles Jr., E. Rosenow, H. Sebrell, and T. Van Itallie (1970)
JAMA 211, 1358-1361
   Abstract »    PDF »
Cytogenetic Studies in Rats of Cyclohexylamine, a Metabolite of Cyclamate.
M. S. Legator, K. A. Palmer, S. Green, and K. W. Petersen (1969)
Science 165, 1139-1140
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)