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Science 18 April 1969:
Vol. 164. no. 3877, pp. 322 - 323
DOI: 10.1126/science.164.3877.322

Articles

Norepinephrine: Release from Brain by d-Amphetamine in vivo

Laurence A. Carr 1 and Kenneth E. Moore 1

1 Department of Pharmacology, Michigan State University, East Lansing 48823

After injection of H3-norepinephrine into the left lateral cerebral ventricle of cats, the lateral and third cerebral ventricles were perfused with an artificial cerebrospinal fluid. Addition of d-amphetamine to the perfusion fluid caused a significant increase in the concentration of H3-norepinephrine in the effluent.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)