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Science 18 April 1969:
Vol. 164. no. 3877, pp. 316 - 318
DOI: 10.1126/science.164.3877.316
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Articles

Graft versus Host Inhibition: Fetal Liver and Thymus Cells to Minimize Secondary Disease

Mortimer M. Bortin 1 and Edward C. Saltzstein 1

1 May and Sigmund Winter Research Laboratory, Mount Sinai Hospital, 948 North 12th Street, Milwaukee, Wisconsin 53233

Long-lived radiation chimeras were produced in mice diflering at the major histocompatibility locus. Survival occurred in lethally irradiated recipients inoculated with allogeneic fetal liver and allogeneic fetal thymus cells in combination. The survival rate was equal or superior to that of mice with transplanted syngeneic fetal, neonatal, or adult hematopoietic cells.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Graft versus Leukemia: Quantification of Adoptive Immunotherapy in Murine Leukemia.
M. M. Bortin, A. A. Rimm, and E. C. Saltzstein (1973)
Science 179, 811-813
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Science. ISSN 0036-8075 (print), 1095-9203 (online)