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Science 4 April 1969:
Vol. 164. no. 3875, pp. 70 - 71
DOI: 10.1126/science.164.3875.70
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Articles

Endocrine Control of Adrenal Progesterone Secretion in the Ovariectomized Rat

John A. Resko 1

1 Department of Reproductive Physiology and Behavior, Oregon Regional Primate Research Center, Beaverton 97005

In the ovariectomized rat, the adrenal gland secretes progesterone. Adrenocorticotropin treatment elevates concentrations of this steroid in plasma, and inhibitors of adrenocorticotropin or progesterone biosynthesis lower the concentration. Adrenocorticotropin controls progesterone secretion by the adrenal but not by the ovary. Adrenal progesterone and its mode of control may have important influences on reproductive processes.


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