Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 14 March 1969:
Vol. 163. no. 3872, pp. 1225 - 1226
DOI: 10.1126/science.163.3872.1225
Prev | Table of Contents | Next

Articles

Early Experiences Accelerate Maturation of the 24-Hour Adrenocortical Rhythm

Robert Ader 1

1 Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, New York 14620

Rats reared under 12-hour alternating periods of light and dark were killed at times corresponding to the times at which the maximum or minimum plasma corticosterone concentrations occur in mature animals. The characteristic 24-hour adrenocortical rhythm was first observed in rats 21 to 25 days old. In rats handled or stimulated with electric shock, the rhythm developed as early as 16 days.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP..
D J Lavery and U Schibler (1993)
Genes & Dev. 7, 1871-1884
   Abstract »    PDF »
Circadian Corticosteroid Periodicity: Critical Period for Abolition by Neonatal Injection of Corticosteroid.
D. T. Krieger (1972)
Science 178, 1205-1207
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)