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Science 28 February 1969:
Vol. 163. no. 3870, pp. 952 - 953
DOI: 10.1126/science.163.3870.952
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Articles

Direct Pathway to the Brain

Morley R. Kare 1, Paul J. Schechter 2, Sebastian P. Grossman 2, and Lloyd J. Roth 2

1 Monell Chemical Senses Center, University of Pennsylvania, Philadelphia-19103
2 Departments of Pharmacology and Psychology, University of Chicago, Chicago, Illinois 60637

Whole-body autoradiographic stuidies demonstrated that, when isotopically labeled glucose is placed in the ligated oropharynx, there is a rapid movement of the isotope directly to the intracranial cavity. This passage involves nonspecific diflision, bypassing all recognized rouctes to the brain.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)