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Science 28 February 1969:
Vol. 163. no. 3870, pp. 941 - 943
DOI: 10.1126/science.163.3870.941
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Articles

Mitotic Division in Pancreatic Beta Cells

Arthur A. Like 1 and William L. Chick 1

1 E. P. Joslin Research Laboratory, Harvard Medical School, Boston, Massachusetts 02215

Successful expansion of the islet cell mass occurs in genetically diabetic mice (C57 Bl/Ks-dbdb) following a period of dietary restriction, in the absence of a population of precursor cells. Differentiated cells that synthesize insulin retain the capability of undergoing mitotic division.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Genetic Background Determines the Size and Structure of the Endocrine Pancreas.
T. Bock, B. Pakkenberg, and K. Buschard (2005)
Diabetes 54, 133-137
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Science. ISSN 0036-8075 (print), 1095-9203 (online)