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Science 28 February 1969:
Vol. 163. no. 3870, pp. 925 - 926
DOI: 10.1126/science.163.3870.925

Articles

Oxytocin: Crystal Data of a Seleno Analog

Celia C. Chiu 1, Irving L. Schwartz 1, and Roderich Walter 1

1 Department of Physiology, Mount Sinai Medical and Graduate Schools, New York 10029, and Medical Department, Brookhaven National Laboratory, Upton, New York 11973

The sulfur atom in position 6 of deamino-oxytocin (1-beta-mercapto-propionic acid-oxytocin) was replaced by selenium. The crystals of the resulting deamino-6-seleno-oxytocin are similar to those of the "wet" form of deamino-oxytocin, but they are stable upon prolonged exposure to air.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding.
S. Wood, I. Tickle, A. Treharne, J. Pitts, Y Mascarenhas, J. Li, J Husain, S Cooper, T. Blundell, V. Hruby, et al. (1986)
Science 232, 633-636
   Abstract »    PDF »



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