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Science 10 January 1969:
Vol. 163. no. 3863, pp. 187 - 188
DOI: 10.1126/science.163.3863.187
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Articles

Microtubules in Brain Homogenates

Joel B. Kirkpatrick 1

1 Department of Pharmacology, Rutgers Medical School, New Brunswick, New Jersey 08903

Microtubules from neurons are preserved in homogenates of mammalian brain by medium containing organic solvents at acidic pH. By means of negative staining and electron microscopy, the relative concentration of microtubules in suspensions can be assayed. Microtubules from brain have a filamentous and substructure.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)