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Science 27 December 1968:
Vol. 162. no. 3861, pp. 1485 - 1487
DOI: 10.1126/science.162.3861.1485
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Articles

Virus-Like Particles in the Spiral Ganglion of the Guinea Pig Cochlea

Joseph L. Craft 1 and David A. Hilding 1

1 Otologic Research Laboratory, Yale University School of Medicine, New Haven, Connecticut 06510

Double-walled spherical particles 100 millimicrons in diameter were accidentally discovered in the cytoplasm of spiral ganglion neurons of apparently healthy guinea pigs with normal startle responses. These particles in some ways resemble viruses of the herpes group and may represent a latent form of neuronal infection.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)