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Science 13 December 1968:
Vol. 162. no. 3859, pp. 1285 - 1286
DOI: 10.1126/science.162.3859.1285
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Articles

Very-Low-Density Lipoprotein in Intestinal Lymph: Evidence for Presence of the A Protein

Robert K. Ockner 1, Kurt J. Bloch 1, and Kurt J. Isselbacher 1

1 Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston 02114

Rat mesenteric lymph very-low-density lipoproteins of intestinal origin contain components which are antigenically identical to plasma high-density lipoprotein. Because the antigenicity of the latter most likely resides in its apoprotein (the A protein), it is concluded that intestinal very-low-density lipoproteins contain the A protein. This and other evidence supports the concept that the intestine is a source of plasma very-low-density lipoprotein.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)