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Science 1 November 1968:
Vol. 162. no. 3853, pp. 561 - 562
DOI: 10.1126/science.162.3853.561
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Articles

Autoimmune Chorioretinitis in Rhesus Monkeys

Edwin M. Lerner II 1, Sanford H. Stone 1, Ronald E. Myers 2, and Ludwig von Sallmann 3

1 Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20014
2 Laboratory of Perinatal Physiology, National Institute of Neurological Diseases, San Juan, Puerto Rico
3 Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, Bethesda

Monkeys injected with monkey retinal tissue incorporated in Freunld's complete adjuvant developed ocular lesions characterized by choroiditic patches in the fundus periphery and sheathing of retinal vessels. Bovine retina, monkey choroid plexus, and guinea pig kidney were ineffective in this respect.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Homologous Retinal Outer Segment Immunization in Primates: A Clinical and Histopathological Study.
V. G. Wong, W. R. Green, T. Kuwabara, P. R.B. McMaster, and T. P. Cameron (1975)
Arch Ophthalmol 93, 509-513
   Abstract »    PDF »
The Uvea.
T. F. Schlaegel Jr. (1970)
Arch Ophthalmol 84, 391-401
   PDF »
Retinal and Uveal Inflammation in Monkeys Following Inoculation With Homologous Retinal Antigen.
L. von Sallmann, R. E. Meyers, S. H. Stone, and E. M. Lerner II (1969)
Arch Ophthalmol 81, 374-382
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)