Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 4 October 1968:
Vol. 162. no. 3849, pp. 124 - 125
DOI: 10.1126/science.162.3849.124
Prev | Table of Contents | Next

Articles

Epinephrine: Effect on Uptake of Iodine by Dispersed Cells of Calf Thyroid Gland

Morelly L. Maayan 1 and Sidney H. Ingbar 1

1 Boston City Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02118

In isolated thyroid cells I-epinephrine (0.1 and 10.0 micrograms per milliliter), norepinephrine and isoproterenol consistently stimulated the accumulation and organic binding of iodine. The effect was partially inhibited by phentolamine, but not propranolol, and hence may be mediated by alpha receptors. Theophylline did not mimic or enhance the epinephrine effect, suggesting that the latter may not result from activation of adenyl cyclase.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)