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Science 27 September 1968:
Vol. 161. no. 3848, p. 1363
DOI: 10.1126/science.161.3848.1363
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Articles

Transport of 1-Aminocyclopentanecarboxylic Acid from Feline Cerebrospinal Fluid

R. W. P. Cutler 1 and A. V. Lorenzo 1

1 Departments of Neurology and Pharmacology, Harvard Medical School, Children's Hospital Medical Center, Boston, Massachusetts

1-Aminocyclopentanecarboxylic acid was cleared from cerebrospinal fluid of the cat by a saturable mechanism. Clearance was inhibited by naturally occurring neutral amino acids. Carrier transport may explain the low ratio of amino acid in spinal fluid to that in plasma.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Transport of Glycine From the Cerebrospinal Fluid: Factors Regulating Amino Acid Concentration IN Feline Cerebrospinal Fluid.
J. E. Murray and R. W. P. Cutler (1970)
Arch Neurol 23, 23-31
   Abstract »    PDF »
Cerebrospinal Fluid Absorption: In Animals With Experimental Obstructive Hydrocephalus.
A. Sahar, G. M. Hochwald, A. R. Sadik, and J. Ransohoff (1969)
Arch Neurol 21, 638-644
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)