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Science 27 September 1968:
Vol. 161. no. 3848, pp. 1353 - 1354
DOI: 10.1126/science.161.3848.1353
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Articles

Antibodies to Deoxyribonucleic Acid Irradiated with Ultraviolet Light: Detection by Precipitins and Immunofluorescence

Eng M. Tan 1

1 Department of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, California 92037

Two rabbits were immunized with a complex consisting of ultravioietirradiated DNA and methylated bovine serum albumin. Serum antibodies reacted only with irradiated DNA, and the serological reaction was shown by immuneprecipitation and immunofluorescence.


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