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Science 27 September 1968:
Vol. 161. no. 3848, pp. 1344 - 1345
DOI: 10.1126/science.161.3848.1344
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Articles

Inhibitor of Bacterial Growth Released by Human Cells in Culture

C. Paul Kenny 1 and Brlan G. Sparkes 1

1 Laboratory of Hygiene, Department of National Health and Welfare, Ottawa, Canada

Used medium from cultured human cells contains a factor that inhibits growth of the "less virulent" strains of pathogenic bacteria, but only retards growth of the "more virulent" strains. The factor is heat-stable, dialyzable, and unaffected by change in pH; it chromatographs as material of molecular weight between 700 and 1500. There is evidence that this factor is an agr-ketoaldehyde attached to a carrier.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Allelochemics: Chemical Interactions between Species.
R. H. Whittaker and P. P. Feeny (1971)
Science 171, 757-770
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Science. ISSN 0036-8075 (print), 1095-9203 (online)