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Science 13 September 1968:
Vol. 161. no. 3846, pp. 1158 - 1160
DOI: 10.1126/science.161.3846.1158
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Articles

Ecdysones and Analogs: Effects on Development and Reproduction of Insects

W. E. Robbins 1, J. N. Kaplanis 1, M. J. Thompson 1, T. J. Shortino 1, C. F. Cohen 1, and S. C. Joyner 1

1 Entomology Research Division, U.S. Department of Agriculture, Beltsville, Maryland 20705

Ingestion of certain synthetic ecdysone analogs inhibited larval growth and development in several species of insects, whereas 20-hydroxyecdysone was inactive or considerably less active. Natural 20-hydroxyecdysone and ponasterone A, and a synthetic ecdysone analog inhibited ovarian maturation and egg production in the adult housefly. These effects appeared to be related to hormonal activity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
RH 5849, a nonsteroidal ecdysone agonist: effects on a Drosophila cell line.
K. Wing (1988)
Science 241, 467-469
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Ovarian Maturation in Stable Flies: Inhibition by 20-Hydroxyecdysone.
J. E. Wright, W. F. Chamberlain, and C. C. Barrett (1971)
Science 172, 1247-1248
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Ecdysone Analog: Conversion to Alpha Ecdysone and 20-Hydroxyecdysone by an Insect.
J. N. Kaplanis, W. E. Robbins, M. J. Thompson, and A. H. Baumhover (1969)
Science 166, 1540-1541
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Puparium Formation in Flies: Contraction to Puparium Induced by Ecdysone.
P. Berreur and G. Fraenkel (1969)
Science 164, 1182-1183
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