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Science 30 August 1968:
Vol. 161. no. 3844, pp. 904 - 906
DOI: 10.1126/science.161.3844.904
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Articles

Lupus Nephritis: Varying Complement-Fixing Properties of Immuvnoglobulin G Antibodies to Antigens of Cel Nuclei

Takeshi Tojo 1 and George J. Friou 1

1 Department of Medicine, University of Southern California School of Medicine, Los Angeles

Relative complement-fixing activity of antibodies to nuclear antigens, including DNA, were determined in serums of 15 patients with, and 65 patients without, active lupus nephritis, by comparing titers obtained in two methods. High complement-fixing activity of antibody was found in the nephritis group and low activity in the others. Results with immunoglobulin G fractions were similar.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Antibodies to DNA.
B. H. Hahn (1998)
N. Engl. J. Med. 338, 1359-1368
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Section 8: Systemic Lupus Erythematosus.
(1973)
JAMA 224, 701-711
   Abstract »    PDF »
Lupus Erythematosus.
D. L. Tuffanelli (1972)
Arch Dermatol 106, 553-566
   Abstract »    PDF »
The Clinical Course of the Proliferative and Membranous Forms of Lupus Nephritis.
D. S. BALDWIN, J. LOWENSTEIN, N. F. ROTHFIELD, G. GALLO, and R. T. MCCLUSKEY (1970)
Ann Intern Med 73, 929-942
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)