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Science 23 August 1968:
Vol. 161. no. 3843, pp. 791 - 793
DOI: 10.1126/science.161.3843.791
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Articles

Breakdown and Assembly of Polyribosomes in Synchronized Chinese Hamster Cells

David L. Steward 1, Joseph R. Shaeffer 1, and Ronald M. Humphrey 1

1 M.D. Anderson Hospital and Tumor Institute, University of Texas, Houston 77025

Polyribosomes were absent in metaphase Chinese hamster cells and were reassembled after mitosis. This assembly correlated temporally with formation of nuclear membrane and decondensation of chromatin, accounted for a threefold increased rate of protein synthesis, and occurred independently of de novo RNA synthesis, that is, it utilized preexisting messenger RNA.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Poly(A) Polymerase Phosphorylation Is Dependent on Novel Interactions with Cyclins.
G. L. Bond, C. Prives, and J. L. Manley (2000)
Mol. Cell. Biol. 20, 5310-5320
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Cyclin E Associates with Components of the Pre-mRNA Splicing Machinery in Mammalian Cells.
W. Seghezzi, K. Chua, F. Shanahan, O. Gozani, R. Reed, and E. Lees (1998)
Mol. Cell. Biol. 18, 4526-4536
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Science. ISSN 0036-8075 (print), 1095-9203 (online)