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Science 23 August 1968:
Vol. 161. no. 3843, pp. 787 - 789
DOI: 10.1126/science.161.3843.787
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Articles

Visual Pigment Renewal in the Mature Frog Retina

Michael O. Hall 1, Dean Bok 2, and A. D. E. Bacharach 3

1 Jules Stein Eye Institute, University of California Medical Center, Los Angeles 90024
2 Jules Stein Eye Institute and Department of Anatomy
3 Jules Stein Eye Institute

It has been demonstrated by autoradiography that radioactive amino acids serve as precursors for proteins which are subsequently incorporated into retinal rod outer segment discs in mature animals. By the isolation and purification of visual pigment from retinas of adult frogs after injection of tritiated leucine and phenylalanine, it has been shown that at least part of this labeled protein consists of visual pigment (rhodopsin).


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene.
J. Gao, K. Cheon, S. Nusinowitz, Q. Liu, D. Bei, K. Atkins, A. Azimi, S. P. Daiger, D. B. Farber, J. R. Heckenlively, et al. (2002)
PNAS 99, 5698-5703
   Abstract »    Full Text »    PDF »
Physiological Chemistry of the Eye.
A. Spector (1970)
Arch Ophthalmol 83, 506-522
   PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)