Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 9 August 1968:
Vol. 161. no. 3841, pp. 576 - 577
DOI: 10.1126/science.161.3841.576
Prev | Table of Contents | Next

Articles

Ionic Interaction of Sulfatide with Choline Lipids

Morris B. Abramson 1 and Robert Katzman 1

1 Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York 10461

Aqueous systems of sphingomyelin-sulfatide and lecithin-sulfatide were compared with aqueous systems of the individual lipids. The acid capacity of the mixed lipids increased, a result of the formation of an ionic bond between the sulfate of one molecule and the positive nitrogen of the other, making the phosphate available for direct titration. Cholesterol reduces this ionic interaction, probably because of the increased spacing of the ionized groups.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)