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Science 9 August 1968:
Vol. 161. no. 3841, pp. 572 - 573
DOI: 10.1126/science.161.3841.572
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Articles

Temperature in the Monkey: Transmitter Factors Released from the Brain during Thermoregulation

Robert D. Mers 1 and Lawrence G. Sharpe 1

1 Laboratory of Neuropsychology, Purdue University, Lafayette, Indiana 47907

When perfusate is collected from the anterior hypothalamus of a cooled donor monkey and is transfused to a corresponding hypothalamic site in a normal monkey, fever occurs in this recipient. Conversely, perfusate from a heated donor monkey lowers the recipient monkey's temperature when the same hypothalamic transfusion procedure is followed. These experiments provide direct evidence of a neurochemical "coding" within the specific anatomical region of the brain historically implicated in the control of body temperature.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Changes in protein levels in perfusates of freely moving cats: relation to behavioral state.
R. Drucker-Colin, C. Spanis, C. Cotman, and J. McGaugh (1975)
Science 187, 963-965
   Abstract »    PDF »
Pineal Function in Sparrows: Circadian Rhythms and Body Temperature.
S. Binkley, E. Kluth, and M. Menaker (1971)
Science 174, 311-314
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)