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Science 9 August 1968:
Vol. 161. no. 3841, pp. 571 - 572
DOI: 10.1126/science.161.3841.571
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Articles

Histochemical Localization of Renal Trehalase: Demonstration of a Tubular Site

I. William Grossman 1 and Bertram Sacktor 2

1 Department of Pathology, Sinai Hospital, Baltimore, Maryland
2 Gerontology Research Center, National Institute of Child Health and Human Development, Baltimore City Hospitals, Baltimore, Maryland 21224

Trehalase activity has been localized histochemically within the cortical tubules of the human, rabbit, and mouse kidneys. The specific localization of the enzyme supports the hypothesis that trehalase, in concert with a series of other enzymes which synthesize trehalose from glucose, functions in a mechanism for the reabsorption of glucose from the glomerular filtrate.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)