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Science 2 August 1968:
Vol. 161. no. 3840, pp. 487 - 489
DOI: 10.1126/science.161.3840.487
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Articles

Rhodopsin Photoproducts: Effects on Electroretinogram Sensitivity in Isolated Perfused Rat Retina

Robert N. Frank 1 and John E. Dowling 1

1 Wilmer Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205

Isolated perfused retinas of albino rats were exposed to brief saturating flashes of white light which bleached about 50 percent of the rhodopsin present. Transient photoproducts of the reaction could be detected for about 30 minutes. The b-wave threshold increased by some 3 logarithmic units immediately after the flash and remained stable at this level thereafter. This suggests that the longer-lived intermediate products of rhodopsin photolysis do not influence scotopic visual sensitivity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Adaptation in Retinal Rods of Axolotl: Intracellular Recordings.
S. R. Grabowski, L. H. Pinto, and W. L. Pak (1972)
Science 176, 1240-1242
   Abstract »    PDF »
Optics and Visual Physiology.
R. E. Carr (1970)
Arch Ophthalmol 84, 238-251
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Science. ISSN 0036-8075 (print), 1095-9203 (online)