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Science 26 July 1968:
Vol. 161. no. 3839, pp. 379 - 381
DOI: 10.1126/science.161.3839.379
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Articles

Antigenic Specificities Related to the Cold Agglutinin Activt of Gamma M Globulins

Ralph C. Williams Jr. 1, Henry G. Kunkel 2, and J. Donald Capra 2

1 Department of Medicine, University Hospitals, Minneapolis, Minnesota
2 Rockefeller University, New York

Certain antiserums prepared against isolated cold agglutinins demonstrate specificity for gamma M globulins with this activity and not for similar gamma M globulins lacking such activity. The cold agglutinin specific antigens fall into several major and minor groups. Their exact relation to the presumed antibody-combining sites remains to be determined.


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