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Science 19 July 1968:
Vol. 161. no. 3838, pp. 286 - 288
DOI: 10.1126/science.161.3838.286
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Articles

Feeding and Core Temperature in Albino-Rats: Changes Induced by Preoptic Heating and Cooling

N. Herbert Spector 1, John R. Brobeck 1, and Charles L. Hamilton 1

1 Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia 19104, and Veterans Administration Hospital, Coatesville, Pennsylvania 19320

At an ambient temperature of 25°C, selective cooling of the area preoptica medialis to 24 ° ± 1°C produced a significant decrease in food intake together with hyperthermia. Heating the same area to 43° ± 1°C resulted in the opposite effects. At an ambient temperature of 35°C, heating the area preoptica medialis to 43°C resulted in a decrease in food intake despite concomitant hypothermia.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)