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Articles
Lymphocytes: Circulation Altered by Trypsin
1 Department of Medicine, New York University School of Medicine, New York 10016
Rat thoracic duct lymphocytes altered by trypsin in vitro do not circulate normally. At early intervals after transfusion of lymphocytes labeled with chromium-51 selective accumulation of radioactivity in the lymph nodes is abolished, while uptake in the spleen is not reduced. Later, the cells appear to "home" to lymph nodes and recirculate to the lymph.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)