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Science 12 July 1968:
Vol. 161. no. 3837, pp. 176 - 178
DOI: 10.1126/science.161.3837.176

Articles

Lymphocytes: Circulation Altered by Trypsin

Judith Woodruff 1 and Bertram M. Gesner 1

1 Department of Medicine, New York University School of Medicine, New York 10016

Rat thoracic duct lymphocytes altered by trypsin in vitro do not circulate normally. At early intervals after transfusion of lymphocytes labeled with chromium-51 selective accumulation of radioactivity in the lymph nodes is abolished, while uptake in the spleen is not reduced. Later, the cells appear to "home" to lymph nodes and recirculate to the lymph.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Liver Damage Preferentially Results from CD8+ T Cells Triggered by High Affinity Peptide Antigens.
J. Q. Russell, G. J. Morrissette, M. Weidner, C. Vyas, D. Aleman-Hoey, and R. C. Budd (1998)
J. Exp. Med. 188, 1147-1157
   Abstract »    Full Text »    PDF »
Glucocorticosteroid Therapy: Mechanisms of Action and Clinical Considerations.
A. S. FAUCI, D. C. DALE, and J. E. BALOW (1976)
Ann Intern Med 84, 304-315
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)