Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 5 July 1968:
Vol. 161. no. 3836, pp. 57 - 59
DOI: 10.1126/science.161.3836.57
Prev | Table of Contents | Next

Articles

Cyclic 3',5'-Adenosine Monophosphate Phosphodiesterase Produced by the Slime Mold Dictyostelium discoideum

Ying-Ying Chang 1

1 Department of Biology, Princeton University, Princeton, New Jersey 08540

An enzyme that hydrolyzes cyclic ',5'-adenosine monophosphate to 5'-adenosine monophosphate was found in the culture medium of the cellular slime mold Dictyostelium discoidum. The enzymatic activity shows a pH optimum of 7.5, and magnesium is required for maximum activity. The enzyme is not inhibited by caffeine. It has a Michaelis-Menten constant of 2 x 10-3M and its molecular weight is around 300,000.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Adenosine 3', 5'-Monophosphate Phosphodiesterase in the Growth Medium of Physarum polycephalum.
A. W. Murray, M. Spiszman, and D. E. Atkinson (1971)
Science 171, 496-498
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)