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Science 21 June 1968:
Vol. 160. no. 3834, pp. 1357 - 1358
DOI: 10.1126/science.160.3834.1357
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Articles

Hereditary Autoimmune Thyroiditis in the Fowl

R. K. Cole 1, Joseph H. Kite Jr. 2, and Ernest Witebsky 2

1 Department of Poultry Science, Cornell University,Ithaca, New York 14850
2 Department of Microbiology, State University of New York at Buffalo, Buffalo 14214

In the Cornell C strain of White Leghorn chickens, thyroiditis appeared spontaneously. It was characterized by phenotypic changes due to a decrease of thyroxine, histological damage to the thyroid gland, and the presence in the seruim of antibodies to thyroglobulin. Susceptibility to the disease is genetically inherited. Hormonal bursectomy (androgen given to the embryo) suppresses the development of thyroiditis.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)