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Science 21 June 1968:
Vol. 160. no. 3834, pp. 1346 - 1348
DOI: 10.1126/science.160.3834.1346
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Articles

Virus-Directed Protein Synthesis in Different Animal and Human Cells

John J. Holland 1

1 Department of Molecular and Cell Biology, University of California, Irvine 92664

The relative proportions of viral gene products (viral proteins) that are synthesized in different types of animal cells infected with the same RNA virus inoculum were compared. The relative rates of synthesis of the various virus proteins late in infection were remarkably constant regardless of cell type infected. This was true in cell lines that produced only small amounts of virus and virus proteins, as well as in those that gave large yields of viruses and virus proteins.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)