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Science 14 June 1968:
Vol. 160. no. 3833, pp. 1243 - 1244
DOI: 10.1126/science.160.3833.1243
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Articles

Transverse Tubular System in Glycerol-Treated Skeletal Muscle

Brenda Eisenberg 1 and R. S. Eisenberg 1

1 Department of Physiology, Duke University Medical Center, Durham, North Carolina 27706

Horseradish peroxidase used as an extracellular marker fills 98.5 percent of the central triadic elements (tubules) in normal muscle and 97.2 percent in muscle soaked in Ringer solution to which 400-millimolar glycerol is added. A glycerol-soaked muscle rapidly returned to normal Ringer solution has a disrupted transverse tubular system and has only 3.2 percent of triads filled with peroxidase.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Excitation-Contraction Uncoupling: The Effect of Hyperosmolar Glycerol Solution and Dantrolene Sodium on Mammalian Muscle in Vitro.
T. Kurihara and J. E. Brooks (1975)
Arch Neurol 32, 92-97
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