Motor Effects of Copper in the Caudate Nucleus: Reversible Lesions with Ion-Exchange Resin Beads
Larry L. Butcher 1 and
Stephen S. Fox 1
1 Department of Psychology and Mental Health Research Institute, University of Michigan, Ann Arbor
A method employing the use of ion-exchange resin beads is described for the punctate introduction of discrete amounts of various anions, cations, or zwitterions into given brain regions. A series of experiments utilizing the method to introduce ionic copper into the caudate nucleus with the resulting motor manifestations are discussed.