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Science 24 May 1968:
Vol. 160. no. 3830, pp. 888 - 890
DOI: 10.1126/science.160.3830.888
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Articles

Agent of Disease Contracted from Green Monkeys

Robert E. Kissling 1, Roslyn Q. Robinson 1, Frederick A. Murphy 1, and Sylvia G. Whitfield 1

1 Virology Section, National Communicable Disease Center, Atlanta, Georgia 30333

An infectious agent obtained from patients who became ill after exposure to tissues of African green monkeys is viral in character. By electron microscopy, the agent appeared cylindrical, 90 to 100 nanometers in diameter, and 130 to 2600 nanometers in length. Cross-striations at 5-nanometer intervals and a core diameter of 45 nanometers were observed. The agent was completely resistant to the effects of the metabolic inhibitor 5-bromodeoxyuridine, which may mean that RNA is the genetic material. It was sensitive to ether and relatively sensitive to destruction by heat.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Emerging Viral Infections.
R. T. Johnson (1996)
Arch Neurol 53, 18-22
   Abstract »    PDF »
Green Monkey Disease ("Marburg Virus" Disease): A New Zoonosis.
J. P. LUBY and C. V. SANDERS (1969)
Ann Intern Med 71, 657-660
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)