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Science 19 April 1968:
Vol. 160. no. 3825, pp. 327 - 328
DOI: 10.1126/science.160.3825.327
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Articles

Nerves in Cortical Bone

Reginald R. Cooper 1

1 Departmenit of Orthopedics, University of Iowa College of Medicine, Iowa City

Modified electron-microscopic techniques permit the sectioning of fully mineralized compact bone. Cortical canals in human femur are extensively innervated. Most nerves are unmyelinated and range from 0.5 to 10 micrometers in diameter. I have found a few mixed nerves (myelinated and unmyelinated fibers), one of which was 130 micrometers in diameter.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)