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Science 12 April 1968:
Vol. 160. no. 3824, pp. 203 - 204
DOI: 10.1126/science.160.3824.203
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Articles

Adenosine Triphosphate and Adenosine Triphosphatase in Hormone-Containing Granules of Posterior Pituitary Gland

Alan M. Poisner 1 and William W. Douglas 1

1 Department of Pharmacology, Albert Einstein College of Medicine, New York

Neurosecretory granules prepared from bovine posterior pituitary glands by cell fractionation methods contain adenosine triphosphate and adenosine triphosphatase activity. Addition of adenosine triphosphate to suspensions of granules stimulates release of vasopressin. It is suggested that adenosine triphosphate and adenosine triphosphatase participate in the storage and release of vasopressin.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)