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Science 5 April 1968:
Vol. 160. no. 3823, pp. 95 - 96
DOI: 10.1126/science.160.3823.95

Articles

Cerebral Synaptic Transmission and Behavioral Effects of Dimethoxyphenylethylamine: A Potential Psychotogen

Lucio Vacca 1, Masamoto Fujimori 1, Scott H. Davis 1, and Amedeo S. Marrazzi 1

1 Department of Pharmacology, University of Minnesota, Minneapolis

Dimethoxyphenylethylamine, like mescaline which it resembles, impairs cerebral synaptic transmission and behavior in cats. It has properties associated with hallucinogens and, on this score, qualifies as a potential inducer of psychosis. The idea of such an endogenous inducer is thus reaffirmed by the candidacy of dimethoxyphenylethylamine.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)