Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 23 February 1968:
Vol. 159. no. 3817, pp. 880 - 881
DOI: 10.1126/science.159.3817.880
Prev | Table of Contents | Next

Articles

Immunosuppressant from Group A Streptococci

Artin Malakian 1 and John H. Schwab 1

1 Department of Bacteriology and Immunology, University of North Carolina Medical School, Chapel Hill

A cytoplasmic component of group A streptococci suppresses both 19S and 7S antibody responses of mice to sheep erythrocytes. Partial purification is achieved by differential centrifugation and gel filtration. When the direct and indirect hemolytic plaque techniques are used, a single injection of this group A material given before injection of erythrocytes produces more than 90-percent suppression of either primary or secondary immune response.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)