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Science 19 January 1968:
Vol. 159. no. 3812, pp. 319 - 320
DOI: 10.1126/science.159.3812.319
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Articles

Ethanol-1-C14 Metabolism in Alcoholics and Nonalcoholics

Jack H. Mendelson 1

1 National Center for Prevention and Control of Alcoholism, National Institute of Mental Health, Chevy Chase, Maryland

Metabolism of ethanol-1-C14 was assessed in a group of alcoholic and nonalcoholic male subjects. All subjects were screened for absence of physical derangement. Subjects were also carefully matched by dietary, social, and environmental criteria. No differences in rate of output of Cl4CO2 were detected after ingestion of alcohol which produced concentrations of 50 to 60 milligrams of alcohol per 100 milliliters of blood. These data do not support the hypothesis that alcoholics metabolize ethanol more rapidly than nonalcoholics do.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Chimpanzee as an Animal Model for Investigating Alcoholism.
W. A. Pieper, M. J. Skeen, H. M. McClure, and P. G. Bourne (1972)
Science 176, 71-73
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Science. ISSN 0036-8075 (print), 1095-9203 (online)