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Science 12 January 1968:
Vol. 159. no. 3811, p. 217
DOI: 10.1126/science.159.3811.217
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Articles

Macrophage Cultures: An Extracellular Esterase

Edith Wiener 1 and Daniel Levanon 1

1 Department of Microbiological Chemistry, Hebrew University- Hadassah Medical School, Jerusalem, Israel

An enzyme having esterase activity accumulates in the culture media of mouse peritoneal mononuclear leukocytes during differentiation of the cells into macrophages. It has a pH optimum of 6.5 and shows aryl esterase characteristics. The esterase differs from another macrophage hydrolase, acid phosphatase, in its mainly extracellular distribution.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)