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Science 5 January 1968:
Vol. 159. no. 3810, pp. 91 - 93
DOI: 10.1126/science.159.3810.91
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Articles

Collagen Synthesis by Cells Synchronously Replicating DNA

Lois M. Davies 1, Jean H. Priest 1, and Robert E. Priest 1

1 Department of Pathology, University of Colorado Medical Center, Denver

Replication and the performance of a differentiated function have been considered antagonistic processes. When cells in culture are partially tially synchronized with 5-fluoro-2'-deoxyuridine (FUdR), the synthesis of the specialized protein (collagen) is not reduced during chromosomal replication (S period). Collagen synthesis varies with general protein synthesis through the S period.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
In Memoriam: Robert E. Priest--Experimental Pathologist and Teacher (1926-2001).
G. M. Martin (2002)
Am. J. Pathol. 160, 1905
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Protein Synthesis: Its Control in Erythropoiesis.
P. A. Marks and R. A. Rifkind (1972)
Science 175, 955-961
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