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Articles
Induction and Survival of Hemoglobin-Less and Erythrocyte-Less Tadpoles and Young Bullfrogs
1 Department of Chemistry and Institute of Molecular Biophysics, Florida State University, Tallahassee
Injection of two 25-microgram-per-gram doses of the hemolytic agent phenylhydrazine reduced the hemoglobin level and the erythrocyte count to less than 1 percent of normal tadpole and young blullfrog blood. These anemic animals survive for weeks with little change in overall metabolism. A slow recovery of hemoglobin levels was observed. The implications of this observation for comparative biochemistry are considered.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)