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Science 22 December 1967:
Vol. 158. no. 3808, pp. 1589 - 1590
DOI: 10.1126/science.158.3808.1589
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Articles

Renin-Like Enzyme in the Adrenal Gland

James W. Ryan 1

1 Department of the Regius Professor of Medicine, University of Oxford, Oxford, England

The rabbit adrenal gland contains an enzyme which reacts with renin substrate to form a vasopressor polypeptide, probably angiotensin I. In view of the strong effects of angiotensin on secretion of aldosterone and catecholamine, this finding suggests that there may be an intra-adrenal mechanism for the control of adrenal secretions.


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Intraadrenal Interactions in the Regulation of Adrenocortical Steroidogenesis.
M. Ehrhart-Bornstein, J. P. Hinson, S. R. Bornstein, W. A. Scherbaum, and G. P. Vinson (1998)
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