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Science 15 December 1967:
Vol. 158. no. 3807, pp. 1455 - 1457
DOI: 10.1126/science.158.3807.1455
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Articles

Transforming Activity of Green Monkey SA7 (C8) Adenovirus in Tissue Culture

A. D. Altstein 1, O. F. Sarycheva 1, and N. N. Dodonova 1

1 L. A. Tarassevich State Control Institute for Medical Biological Preparations, Moscow, U.S.S.R.

Simian SA7 (C8) adenovirus can effect transformation of mouse, rat, and hamster cells in tissue culture. The transforming activity of the virus was more pronounced in culture medium containing 0.1 millimolar CaCl2, a lower concentration than that usually used. The transformed hamster cells were tumorigenic in hamsters.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)