Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 24 November 1967:
Vol. 158. no. 3804, pp. 1061 - 1064
DOI: 10.1126/science.158.3804.1061
Prev | Table of Contents | Next

Articles

Murine Lymphoma: Augmented Growth in Mice with Pertussis Vaccine-Induced Lymphocytosis

M. Hirano 1, J. G. Sinkovics 1, C. C. Shullenberger 1, and C. D. Howe 1

1 Department of Medicine, University of Texas M. D. Anderson Hospital and Tumor Institute, Houston 77025

Injection of Bordetella pertussis vaccine caused an excessive lymphocytosis, associated with an augmented growth of a lymphoma cell homotransplant in mice. A markedly impaired reactive cell proliferation was revealed in the spleens of the vaccine-pretreated mice after stimulation with phytohemagglutinin or Freund's complete adjuvant.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Hemophilia: Role of Organ Homografts.
T. L. Marchioro, C. Hougie, H. Ragde, R. B. Epstein, and E. D. Thomas (1969)
Science 163, 188-190
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)