Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 13 October 1967:
Vol. 158. no. 3798, pp. 265 - 267
DOI: 10.1126/science.158.3798.265
Prev | Table of Contents | Next

Articles

Congenital Malformations Induced by Mescaline, Lysergic Acid Diethylamide, and Bromolysergic Acid in the Hamster

William F. Geber 1

1 Department of Pharmacology, Medical College of Georgia, Augusta

Malformations of the brain, spinal cord, liver, and other viscera; body edema; and localized hemorrhages were found in fetal hamsters from mothers injected subcutaneously with a single dose of mescaline, lysergic acid diethylamide, or 2-bromo-D lysergic acid diethylamide on the 8th day of pregnancy. In addition, all three drugs produced an increase in the percentages of small fetuses per litter, of resorptions, and of fetal mortality.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Possible Reproductive Detriment in LSD Users.
C. B. Jacobson and C. M. Berlin (1972)
JAMA 222, 1367-1373
   Abstract »    PDF »
Brain and Eye Abnormalities: Possible Sequelae to Prenatal Use of Multiple Drugs Including LSD.
B. Bogdanoff, L. B. Rorke, M. Yanoff, and W. S. Warren (1972)
Arch Pediatr Adolesc Med 123, 145-148
   Abstract »    PDF »
Social and Medical Aspects of Illicit Use of LSD.
J. Buckman (1971)
International Journal of Social Psychiatry 17, 163-176
   PDF »
LSD and Genetic Damage.
N. I. Dishotsky, W. D. Loughman, R. E. Mogar, and W. R. Lipscomb (1971)
Science 172, 431-440
   Abstract »    PDF »
LSD: No Teratogenic Action in Rats, Mice, and Hamsters.
C. Roux, R. Dupuis, and M. Aubry (1970)
Science 169, 588-589
   Abstract »    PDF »
Effect of LSD on Human Pregnancy.
W. H. McGlothlin, R. S. Sparkes, and D. O. Arnold (1970)
JAMA 212, 1483-1487
   Abstract »    PDF »
In Vivo Effects of Illicit Hallucinogens on Human Lymphocyte Chromosomes.
D. Dorrance, O. Janiger, and R. L. Teplitz (1970)
JAMA 212, 1488-1491
   Abstract »    PDF »
LSD and Chromosomes: A Controlled Experiment.
J.-H. Tjio, W. N. Pahnke, and A. A. Kurland (1969)
JAMA 210, 849-856
   Abstract »    PDF »
LSD: Autoradiographic Study on the Placental Transfer and Tissue Distribution in Mice.
J. E. Idanpaan-Heikkila and J. C. Schoolar (1969)
Science 164, 1295-1297
   Abstract »    PDF »
Lysergic Acid Diethylamide: Effects on the Developing Mouse Lens.
J. K. Hanaway (1969)
Science 164, 574-575
   Abstract »    PDF »
Drug Dependency: Investigations of Stimulants and Depressants.
A. KALES, G. HEUSER, J. D. KALES, W. H. RICKLES JR., R. T. RUBIN, M. B. SCHARF, J. T. UNGERLEIDER, and W. D. WINTERS (1969)
Ann Intern Med 70, 591-614
   Abstract »    PDF »
Medical Complications of Pleasure-Giving Drugs.
D. B. Louria (1969)
Arch Intern Med 123, 82-87
   Abstract »    PDF »
Cytogenetic Effects of LSD 25 Therapy in Man.
D. A. Hungerford, K. M. Taylor, C. Shagass, G. U. LaBadie, G. B. Balaban, and G. R. Paton (1968)
JAMA 206, 2287-2291
   Abstract »    PDF »
Chromosomal Damage in LSD Users.
J. Egozcue, S. Irwin, and C. A. Maruffo (1968)
JAMA 204, 214-218
   Abstract »    PDF »
Beards, Flowers, Drugs, and Love.
J. R. E. (1967)
Ann Intern Med 67, 1341-1343
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)